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Search Results for " Epidermal growth factor receptor "

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201

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天然化合物

130

リコンビナントタンパク質

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カタログ番号	製品名	別名	ターゲット
T21723L	Epidermal Growth Factor Receptor Peptide Acetate	Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)	Others
	Epidermal Growth Factor Receptor Peptide Acetate (Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)) exists on the cell surface and is activated by the binding of its specific ligands.EGFR belongs t...		Others
TP2229	Epidermal growth factor receptor (994-1002) acetyl/amide		Others
	The epidermal growth factor receptor is the cell-surface receptor for members of the epidermal growth factor family of extracellular protein ligands.		Others
T3466	FIIN-3		EGFR , FGFR
	FIIN-3 is an irreversible inhibitor of FGFR.		EGFR , FGFR
T5475	ZD-4190		EGFR , VEGFR
	ZD-4190 is a compound that inhibits both the vascular endothelial growth factor receptor 2 (VEGFR2) and the epidermal growth factor receptor (EGFR) signaling pathways, utilized in cancer treatment.		EGFR , VEGFR
T2705	Mutant EGFR inhibitor		EGFR
	Mutant EGFR inhibitor is a selective and potent Mutated EGFR inhibitor, inhibits L858R activating mutant, the Exonl9 deletion activating mutant and the T790M resistance mutant.		EGFR
T8976	PD-089828		EGFR , FGFR , PDGFR , Src
	PD 089828 is a competitive inhibitor of the receptor tyrosine kinases FGFR1, PDGFRβ, and EGFR (IC50s = 0.15, 1.76, and 5.47 µM, respectively) and a noncompetitive inhibitor of the nonreceptor tyrosine kinase c-Src (IC50 ...		EGFR , FGFR , PDGFR , Src
T11160	EGFR-IN-5		EGFR
	EGFR-IN-5 is a EGFR inhibitor, EGFR-IN-5 with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively.		EGFR
T23127	PD-161570	PD 161570	EGFR , FGFR , PDGFR , Src
	PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...		EGFR , FGFR , PDGFR , Src
T16343	NRC-2694		EGFR
	NRC-2694 is an antagonist of the epidermal growth factor receptor (EGFR). It has anti-cancer and anti-proliferative properties.		EGFR
T23176	PP 3		Src
	PP 3 is a Negative control for the Src kinase inhibitor PP 2		Src
T10534	BI-4020		EGFR
			EGFR
T7819	TAS0728		EGFR , HER
	TAS0728 is a HER2 inhibitor, with antitumor activity		EGFR , HER
T2491	AZ-5104		EGFR
	AZ5104 is a potent EGFR inhibitor.		EGFR
T11162	EGFR-IN-8		EGFR , c-Met/HGFR
			EGFR , c-Met/HGFR
T5410	PD158780		EGFR
	PD 158780 reversibly inhibits auto and transphosphorylation of all four members of the ErbB receptor superfamily: EGFR, ErbB2, ErbB3, and ErbB4 (IC50s: 8μM, 49 nM, 52 nM, and 52 nM in cell assay).		EGFR
T6733	WZ-3146		EGFR
	WZ3146 is a mutant-selective irreversible inhibitor of EGFR(L858R) and EGFR(E746_A750) with IC50 of 2 nM and 2 nM; does not inhibit ERBB2 phosphorylation (T798I).		EGFR
T6824	EAI045		EGFR
	EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.		EGFR
T6238	WZ4002		EGFR
	WZ4002 is a mutant-selective EGFR inhibitor for EGFR(L858R) and EGFR(T790M) with IC50 of 2 nM/8 nM.		EGFR
T17182	TX1-85-1		EGFR
	TX1-85-1 induces partial degradation of Her3 protein and attenuates Her3-dependent signaling. TX1-85-1 is an irreversible Her3 inhibitor (IC50: 23 nM). TX1-85-1 is also the first selective Her3 ligand, which forms a cova...		EGFR
T11569	HKI-357		EGFR
			EGFR
T9912	Trastuzumab		EGFR
	Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastr...		EGFR
T3659	Zorifertinib	AZD3759	EGFR
	Zorifertinib (AZD3759) is an orally active, effective and central nervous system-penetrant EGFR inhibitor. The IC50 values were 0.2, 0.3 and 0.2 nM for EGFR L858R mutant, TK wild-type, and Exon 19Del enzymes, respectivel...		EGFR
T6008	CNX-2006	CNX 2006,CNX2006	EGFR
	CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR.		EGFR
T2034	AG1557	AG-1557,AG 1557	EGFR , HER
	AG1557 (AG-1557) is an inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase (pIC50: 8.194).		EGFR , HER
TQ0092	Naquotinib	ASP8273	EGFR
	Naquotinib (ASP8273) (ASP8273) is an orally available, mutant-selective and irreversible EGFR inhibitor; (IC50s: 8-33 nM and 230 nM toward EGFR mutants and EGFR.		EGFR
T6734	WZ8040		EGFR
	WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).		EGFR
T4296	MTX-211	MTX 211	EGFR , PI3K
	MTX-211, an inhibitor of EGFR and PI3K, is used for the therapy of cancer and other diseases.		EGFR , PI3K
T2032	WHI-P180	Janex 3	EGFR , VEGFR , c-RET , CDK
	WHI-P180 (Janex 3) is a potent EGFR and Cdk2 inhibitors with IC50 of 4.0 and 1.0 uM, respectively.		EGFR , VEGFR , c-RET , CDK
T13564	AZ7550		MLK , FAK , EGFR , FLT , Tyrosine Kinases , PYK2 , MNK , IGF-1R , ACK , BTK , ALK , Drug Metabolite
	AZ7550, an active metabolite of AZD9291, inhibits the activity of IGF1R (IC50: 1.6 μM).
T11161	EGFR-IN-7	TQB3804	EGFR
	EGFR-IN-7 (TQB3804) is a selective and potent EGFR kinase inhibitor.		EGFR
T8431	JCN037		EGFR
	JCN037 is potent, non-covalent and brain-penetrant inhibitor of EGFR(EGFR, p-wtEGFR and pEGFRvⅢ with IC50 of 2.49 nM, 3.95 nM, 4.48 nM , respectively).		EGFR
T16369	O-Desmethyl gefitinib		EGFR
	O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 acti...		EGFR
T5437	Gefitinib-based PROTAC 3		EGFR
	Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a VHL ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectivel...		EGFR
T8534	Tyrphostin AG 112		EGFR
	Tyrphostin AG 112 is an inhibitor of EGFR phosphorylation.		EGFR
T3108	CUDC-101	CUDC 101,CUDC101	EGFR , HER , HDAC
	CUDC-101 is a potent inhibitor of HDAC, EGFR and HER2 with IC50s of 4.4, 2.4 and 15.7 nM, respectively.		EGFR , HER , HDAC
T13088	Tarloxotinib bromide	TH-4000	EGFR , HER
			EGFR , HER
T6932	PD168393		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
	PD168393 is an irreversible EGFR inhibitor (IC50: 0.70 nM), irreversibly alkylate Cys-773; inactive against PKC, FGFR, PDGFR, and insulin.		Apoptosis , EGFR , FGFR , IGF-1R , PDGFR , PKC , Autophagy
T22431	SU5204	3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one	EGFR , VEGFR , HER
	SU5204 (3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one), an analogue of SU5025, pharmacologically inhibits VEGFR2(IC50s of 4 and 51.5 μM for FLK-1 (VEGFR-2) and HER2)		EGFR , VEGFR , HER
T6092	Sapitinib	AZD-8931	EGFR
	Sapitinib (AZD-8931) , a reversible, ATP competitive inhibitor of EGFR(IC50=4 nM), ErbB2(IC50=3 nM) and ErbB3(IC50=4 nM), is more effective over Gefitinib or Lapatinib against NSCLC cell, 100-fold more specific for the E...		EGFR
T6908	NSC 228155	NSC228155	EGFR , Epigenetic Reader Domain , DNA/RNA Synthesis , Histone Acetyltransferase
	NSC 228155 is an activator of EGFR, binding to the sEGFR dimerization domain II and modulate EGFR tyrosine phosphorylation.
T6124	Mubritinib	TAK-165	EGFR , FGFR , JAK , PDGFR
	Mubritinib (TAK-165) (TAK-165) is a potent inhibitor of HER2/ErbB2 with IC50 of 6 nM.		EGFR , FGFR , JAK , PDGFR
T6039	TAK-285	TAK285,TAK 285	EGFR , MEK , HER , Aurora Kinase
	TAK-285 is a novel dual HER2 and EGFR(HER1) inhibitor with IC50 of 17 nM and 23 nM, >10-fold selectivity for HER1/2 than HER4, less potent to MEK1/5, c-Met, Aurora B, Lck, CSK etc. Phase 1.		EGFR , MEK , HER , Aurora Kinase
T22396	PF-6274484	PF 6274484	EGFR
	PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R/T790M in H1975 cells with IC50 of 5.8 nM and ...		EGFR
T21853	(E)-AG 556		EGFR
	AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.		EGFR
T9927	Panitumumab		EGFR
	Panitumumab is a fully human IgG2 monoclonal antibody targeting the epidermal growth factor receptor EGFR).		EGFR
TQ0166	Tesevatinib	KD-019,XL-647,EXEL-7647	EGFR , VEGFR , FLT , Ephrin Receptor
	Tesevatinib (XL-647) is an orally available, multi-target tyrosine kinase inhibitor (IC50s: 0.3, 16, 1.5, 8.7, and 1.4 nM for EGFR, ErbB2, KDR, Flt4, and EphB4).		EGFR , VEGFR , FLT , Ephrin Receptor
T4015	HG-14-10-04		ALK
	HG-14-10-04 is a potent and specific ALK inhibitor.		ALK
T8151	Mobocertinib	tak788	EGFR
	Mobocertinib (tak788) is a potent inhibitor of epidermal growth factor receptor (EGFR) and an antineoplastic agent		EGFR
T4014	CP-724714	CP724714,CP 724714	Apoptosis , EGFR
	CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2, c-Met etc.		Apoptosis , EGFR
T10419	AV-412	MP412	EGFR
	AV-412 (MP412) is an EGFR inhibitor (EGFR, EGFR T790M, EGFR L858R, EGFR L858R/T790M and ErbB2 with IC50s of 0.75, 0.79, 0.5, 2.3, 19 nM).		EGFR

Compounds

Epidermal Growth Factor Receptor Peptide Acetate

T21723L

Synonym: Epidermal Growth Factor Receptor Peptide Acetate(96249-43-3 Free base)

Target: Others

Epidermal growth factor receptor (994-1002) acetyl/amide

Mutant EGFR inhibitor

Target: EGFR, FGFR, PDGFR, Src

Target: EGFR, FGFR, PDGFR, Src

Target: EGFR, c-Met/HGFR

Synonym: CNX 2006,CNX2006

Target: EGFR

AG1557

T2034

Synonym: AG-1557,AG 1557

Target: EGFR, VEGFR, c-RET, CDK

AZ7550

T13564

Synonym:

Target: MLK, FAK, EGFR, FLT, Tyrosine Kinases, PYK2, MNK, IGF-1R, ACK, BTK, ALK, Drug Metabolite

O-Desmethyl gefitinib

T16369

Synonym:

Target: EGFR

Gefitinib-based PROTAC 3

Synonym: CUDC 101,CUDC101

Target: EGFR, HER, HDAC

Target: Apoptosis, EGFR, FGFR, IGF-1R, PDGFR, PKC, Autophagy

SU5204

T22431

Synonym: 3-[(2-Ethoxyphenyl)methylidene]-1H-indol-2-one

Target: EGFR, VEGFR, HER

Target: EGFR, Epigenetic Reader Domain, DNA/RNA Synthesis, Histone Acetyltransferase

Mubritinib

T6124

Synonym: TAK-165

Target: EGFR, FGFR, JAK, PDGFR

TAK-285

T6039

Synonym: TAK285,TAK 285

Target: EGFR, MEK, HER, Aurora Kinase

Synonym: KD-019,XL-647,EXEL-7647

Target: EGFR, VEGFR, FLT, Ephrin Receptor

Synonym: CP724714,CP 724714

Target: Apoptosis, EGFR

カタログ番号	製品名	別名	ターゲット
TL0016	Sulforaphene		Apoptosis , ERK , EGFR , NF-κB
	Sulforaphene is a natural product isolated from radish seeds, exhibits an ED50 against velvetleaf seedlings approximately 2 x 10 -4 M. Sulforaphene promotes cancer cells apoptosis and inhibits migration via inhibiting EG...		Apoptosis , ERK , EGFR , NF-κB
T22974	Methyl 2,5-dihydroxycinnamate		EGFR
	EGF receptor-associated tyrosine kinases inhibitor		EGFR
TN1440	Beta-Hydroxyisovalerylshikonin		EGFR , Tyrosine Kinases , Prostaglandin Receptor , Src , AMPK , Fatty Acid Synthase
	Beta-Hydroxyisovalerylshikonin is an inhibitor of protein-tyrosine kinases such as v-Src and EGFR, and has been shown to induce apoptosis in several human tumor cell lines. Beta-Hydroxyisovalerylshikonin significantly de...
T3870	Cyasterone	Cyasteron	Apoptosis , EGFR
	Cyasterone (Cyasteron), a natural EGFR inhibitor, can inhibit the growth of A549 and MGC823 cells, via regulating EGFR signaling pathway, it may be a promising anti-cancer agent. Cyasterone has antifeeding activity.		Apoptosis , EGFR
T1431	Khellin	Amicardine,Methafrone,Visammin	EGFR , Others
	Khellin (Methafrone) is a vasodilator that also has bronchodilatory action.		EGFR , Others
T2995	Chrysophanol	3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb	EGFR
	Chrysophanol (Turkey Rhubarb) is an EGFR/mTOR pathway inhibitor, which can be found in rhubarb, and sorrel.		EGFR
T1737	Genistein	NPI 031L	Apoptosis , EGFR , Endogenous Metabolite , Autophagy
	Genistein (NPI 031L) is an isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA TOPOISOMERASES, TYPE II), with antineoplastic and antitumor activities.		Apoptosis , EGFR , Endogenous Metabolite , Autophagy
T4183	Lavendustin A	RG-14355,NSC 678027	EGFR , Tyrosinase
	lavendustin A (RG-14355) is a potent, cell-permeable inhibitor of epidermal growth factor receptor (EGFR) tyrosine kinase.		EGFR , Tyrosinase
T6427	Butein	2’,3,4,4’-tetrahydroxy Chalcone	Apoptosis , EGFR , Others , PDE , Autophagy
	Butein (2’,3,4,4’-tetrahydroxy Chalcone), a plant polyphenol, is isolated from Rhus verniciflua. It can inhibit the activation of protein tyrosine kinase, NF-κB and STAT3, and also can inhibit EGFR.		Apoptosis , EGFR , Others , PDE , Autophagy
T1181	Gefitinib	ZD1839	EGFR , Tyrosine Kinases , Autophagy
	Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell...		EGFR , Tyrosine Kinases , Autophagy
T2851	Daphnetin	7,8-Dihydroxycoumarin,Daphnetol	EGFR , PKA , PKC , Parasite , Autophagy
	Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...		EGFR , PKA , PKC , Parasite , Autophagy
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
TN3711	Corylifol C		ERK , EGFR , p38 MAPK , MEK
	Corylifol C and, to a lesser extent, xanthoangelol are potent protein kinase inhibitors (inhibitory concentration 50% values for epidermal growth factor receptor (EGFR): 1.1 and 4.4 × 10(-6) μg/ml, respectively).		ERK , EGFR , p38 MAPK , MEK
TN2504	1,5-Dihydroxyxanthone		EGFR , AChR
	1,5-Dihydroxyxanthone exhibits the epidermal growth factor receptor (EGFR) -tyrosine kinase inhibitory activity, with the IC50 value of 90.34 nM. It may have anticholinesterase activity on acetylcholinesterase (AChE) and...		EGFR , AChR

天然物製品

Sulforaphene

TL0016

Synonym:

Target: Apoptosis, ERK, EGFR, NF-κB

Methyl 2,5-dihydroxycinnamate

T22974

Synonym:

Target: EGFR

Beta-Hydroxyisovalerylshikonin

TN1440

Synonym:

Target: EGFR, Tyrosine Kinases, Prostaglandin Receptor, Src, AMPK, Fatty Acid Synthase

Cyasterone

T3870

Synonym: Cyasteron

Target: Apoptosis, EGFR

Khellin

T1431

Synonym: Amicardine,Methafrone,Visammin

Target: EGFR, Others

Chrysophanol

T2995

Synonym: 3-Methylchrysazin,Chrysophanic Acid,Turkey Rhubarb

Target: Apoptosis, EGFR, Endogenous Metabolite, Autophagy

lavendustin A

T4183

Synonym: RG-14355,NSC 678027

Target: EGFR, Tyrosinase

Butein

T6427

Synonym: 2’,3,4,4’-tetrahydroxy Chalcone

Target: Apoptosis, EGFR, Others, PDE, Autophagy

Gefitinib

T1181

Synonym: ZD1839

Target: EGFR, Tyrosine Kinases, Autophagy

Daphnetin

T2851

Synonym: 7,8-Dihydroxycoumarin,Daphnetol

Target: EGFR, PKA, PKC, Parasite, Autophagy

Picropodophyllotoxin

T3S0027

Synonym: AXL 1717,Picropodophyllin

Target: ERK, EGFR, p38 MAPK, MEK

1,5-Dihydroxyxanthone

TN2504

Synonym:

Target: EGFR, AChR

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPY-04818	EGFR Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02676	EGFR Protein, Mouse, Recombinant (His)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00742	EGFR Protein, Human, Recombinant (His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-04529	EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-02958	EGFR Protein, Rat, Recombinant (His)	Rat	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-03724	EGFR Protein, Canine, Recombinant (His)	Canine	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06524	EGFR Protein, Feline, Recombinant (His)	Feline	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-00128	EGFR Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00646	EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-00648	EGFR vIII Protein, Human, Recombinant (His)	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPJ-00647	EGFR vIII Protein, Human, Recombinant (hFc)	Human	Human Cells
	The EGFR subfamily of receptor tyrosine kinases is composed of EGFR, ErbB2, ErbB3 and ErbB4. The EGFR shares 43% - 44% aa sequence identity with the ECD of human EGFR subfamily. All these family members are type I transm...
TMPY-05211	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05612	EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05637	EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-01043	EGFR Protein, Human, Recombinant (hFc)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06593	EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-06549	EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)	Human	HEK293
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPY-05258	EGFR Protein, Human, Recombinant (Isoform Viii, hFc)	Human	Baculovirus-Insect Cells
	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR p...
TMPJ-01286	ProHB-EGF Protein, Human, Recombinant (His)	Human	Human Cells
	Heparin-binding EGF-like growth factor (HB-EGF) is a 1216 kDa member of the epidermal growth factor (EGF) family. It possesses an EGFlike domain, and a heparin-binding motif. Mature HBEGF is a soluble peptide that ari...
TMPK-01073	CLEC14A Protein, Human, Recombinant (His)	Human	HEK293
	CLEC14A is a single-pass transmembrane glycoprotein belonging to the vascular expressed C-type lectin family. CLEC14A is found to be expressed in vascular endothelial cells during embryogenesis and is also implicated in ...
TMPJ-00791	HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	ERBB2 belongs to the protein kinase superfamily, Tyr protein kinase family and EGF receptor subfamily. It contains a protein kinase domain. ERBB2 is widely expressed in epithelial cells, and amplification and/or overexpr...
TMPY-05239	HER2/ERBB2 Protein, Human, Recombinant , Biotinylated	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-04698	HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-03719	HER2/ERBB2 Protein, Canine, Recombinant (His)	Canine	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01137	HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-01944	HER2/ERBB2 Protein, Rat, Recombinant (His)	Rat	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-02469	HER2/ERBB2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-04684	HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00636	HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-02314	HER2/ERBB2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00167	HER2/ERBB2 Protein, Human, Recombinant	Human	HEK293
	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth factor (EGF) receptor family. HER2 protein cannot bind growth fa...
TMPY-00399	HER3/ERBB3 Protein, Human, Recombinant	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02477	HER3/ERBB3 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-02365	HER3/ERBB3 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-01389	HER3/ERBB3 Protein, Human, Recombinant (His)	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00246	HER3/ERBB3 Protein, Rhesus, Recombinant	Rhesus	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPJ-00778	HER2/ERBB2 Protein, Human, Recombinant (His)	Human	Human Cells
	Human epidermal growth factor receptor 2 (HER2) is a type of membrane glycoprotein, and belongs to the epidermal growth factor (EGF) receptor family. HER2 plays a key role in development, cell proliferation and different...
TMPY-03024	HER3/ERBB3 Protein, Rat, Recombinant (His)	Rat	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-04956	HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated	Human	HEK293
	ErbB3, also known as Her3(human epidermal growth factor receptor3), is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound glycoprotein has a neuregulin bindin...
TMPY-00664	ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-00403	FGF-7/KGF Protein, Human, Recombinant (His)	Human	E. coli
	Fibroblast growth factor 7 (FGF7) is a member of the fibroblast growth factor (FGF) family of proteins. FGF7 plays an important role in regulating the proliferation, migration, and differentiation of cells. FGF7 is of st...
TMPY-02474	ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-04168	ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)	Cynomolgus,Rhesus	HEK293
	Angiopoietin-2 (ANG 2, or ANGPT2), is a member of the ANG family, which plays an important role in angiogenesis during the development and growth of human cancers. Both ANGPT-1 and ANGPT-2 appear to bind to the tyrosine ...
TMPY-01560	EGF Protein, Human, Recombinant	Human	E. coli
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-01062	EGF Protein, Human, Recombinant (hFc)	Human	HEK293
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-06984	EGF Protein, Mouse, Recombinant (Yeast)	Mouse	Yeast
	EGF is the founding member of the EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. EGF contains 9 EGF-like domains and 9 LDL-receptor class B repeats. ...
TMPY-04125	PTP1B Protein, Human, Recombinant (His)	Human	E. coli
	PTP1B, also known as PTPN1, belongs to the protein-tyrosine phosphatase (PTP) family. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly c...
TMPY-03484	TCPTP Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Tyrosine-protein phosphatase non-receptor type 2, also known as T-cell protein-tyrosine phosphatase, PTPN2 and PTPT, is a cytoplasm protein that belongs to the protein-tyrosine phosphatase family and Non-receptor class 1...
TMPY-01608	Decorin Protein, Human, Recombinant (His)	Human	HEK293
	Decorin is a ubiquitous small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. It belongs to the small leucine-rich proteoglycan (SLRP) family and consists of a core p...
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EGFR Protein, Cynomolgus, Recombinant (His)

TMPY-04818

Species: Cynomolgus

Expression System: HEK293

EGFR Protein, Mouse, Recombinant (His)

TMPY-02676

Species: Mouse

Expression System: HEK293

EGFR Protein, Human, Recombinant (His)

TMPY-00742

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)

TMPY-04529

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Rat, Recombinant (His)

TMPY-02958

Species: Rat

Expression System: HEK293

EGFR Protein, Canine, Recombinant (His)

TMPY-03724

Species: Canine

Expression System: Baculovirus-Insect Cells

EGFR Protein, Feline, Recombinant (His)

TMPY-06524

Species: Feline

Expression System: Baculovirus-Insect Cells

EGFR Protein, Rhesus, Recombinant (hFc)

TMPY-00128

Species: Rhesus

Expression System: HEK293

EGFR vIII Protein, Human, Recombinant (His & Avi), Biotinylated

TMPJ-00646

Species: Human

Expression System: Human Cells

EGFR Protein, Mouse, Recombinant (hFc)

TMPY-02675

Species: Mouse

Expression System: HEK293

EGFR vIII Protein, Human, Recombinant (His)

TMPJ-00648

Species: Human

Expression System: Human Cells

EGFR vIII Protein, Human, Recombinant (hFc)

TMPJ-00647

Species: Human

Expression System: Human Cells

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)

TMPY-05211

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated

TMPY-05612

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated

TMPY-05637

Species: Human

Expression System: Baculovirus-Insect Cells

EGFR Protein, Human, Recombinant (hFc)

TMPY-01043

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform vIII, His & Avi), Biotinylated

TMPY-06593

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-378, His)

TMPY-06549

Species: Human

Expression System: HEK293

EGFR Protein, Human, Recombinant (Isoform Viii, hFc)

TMPY-05258

Species: Human

Expression System: Baculovirus-Insect Cells

proHB-EGF Protein, Human, Recombinant (His)

TMPJ-01286

Species: Human

Expression System: Human Cells

CLEC14A Protein, Human, Recombinant (His)

TMPK-01073

Species: Human

Expression System: HEK293

HER2/ERBB2 Protein, Rat, Recombinant (E. coli, His)

TMPJ-00791

Species: Rat

Expression System: E. coli

HER2/ERBB2 Protein, Human, Recombinant , Biotinylated

TMPY-05239

Species: Human

Expression System: HEK293

HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His)

TMPY-04698

Species: Human

Expression System: HEK293

HER2/ERBB2 Protein, Canine, Recombinant (His)

TMPY-03719

Species: Canine

Expression System: HEK293

HER2/ERBB2 Protein, Human, Recombinant (aa 1-652, His)

TMPY-01137

Species: Human

Expression System: HEK293

HER2/ERBB2 Protein, Rat, Recombinant (His)

TMPY-01944

Species: Rat

Expression System: HEK293

HER2/ERBB2 Protein, Mouse, Recombinant (hFc)

TMPY-02469

Species: Mouse

Expression System: HEK293

HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)

TMPY-04684

Species: Human

Expression System: HEK293

HER2/ERBB2 Protein, Cynomolgus, Recombinant (His)

TMPY-00636

Species: Cynomolgus

Expression System: HEK293

HER2/ERBB2 Protein, Mouse, Recombinant (His)

TMPY-02314

Species: Mouse

Expression System: HEK293

HER2/ERBB2 Protein, Human, Recombinant

TMPY-00167

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant

TMPY-00399

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant (His)

TMPY-02477

Species: Rhesus

Expression System: HEK293

HER3/ERBB3 Protein, Mouse, Recombinant (His)

TMPY-02365

Species: Mouse

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (His)

TMPY-01389

Species: Human

Expression System: HEK293

HER3/ERBB3 Protein, Rhesus, Recombinant

TMPY-00246

Species: Rhesus

Expression System: HEK293

HER2/ERBB2 Protein, Human, Recombinant (His)

TMPJ-00778

Species: Human

Expression System: Human Cells

HER3/ERBB3 Protein, Rat, Recombinant (His)

TMPY-03024

Species: Rat

Expression System: HEK293

HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated

TMPY-04956

Species: Human

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Human, Recombinant (hFc)

TMPY-00664

Species: Human

Expression System: HEK293

FGF-7/KGF Protein, Human, Recombinant (His)

TMPY-00403

Species: Human

Expression System: E. coli

ANGPT2/Angiopoietin-2 Protein, Mouse, Recombinant (His)

TMPY-02474

Species: Mouse

Expression System: HEK293

ANGPT2/Angiopoietin-2 Protein, Cynomolgus, Rhesus, Recombinant (His)

TMPY-04168

Species: Cynomolgus,Rhesus

Expression System: HEK293

EGF Protein, Human, Recombinant

TMPY-01560

Species: Human

Expression System: E. coli

EGF Protein, Human, Recombinant (hFc)

TMPY-01062

Species: Human

Expression System: HEK293

EGF Protein, Mouse, Recombinant (Yeast)

TMPY-06984

Species: Mouse

Expression System: Yeast

PTP1B Protein, Human, Recombinant (His)

TMPY-04125

Species: Human

Expression System: E. coli

TCPTP Protein, Human, Recombinant

TMPY-03484

Species: Human

Expression System: Baculovirus-Insect Cells

Decorin Protein, Human, Recombinant (His)

TMPY-01608

Species: Human

Expression System: HEK293

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カタログ番号	製品名
L2193	Anti-Liver Cancer Compound Library	1816 compounds
	1816 species of compounds related to liver cancer that can be used in anti-liver cancer drug development and pharmacological studies.
L2191	Anti-Breast Cancer Compound Library	1965 compounds
	A unique collection of 1965 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；

ライブラリー

Anti-Liver Cancer Compound Library

L2193

Compounds: 1816

Anti-Breast Cancer Compound Library

L2191

Compounds: 1965